Jenny Mae Samson, Ph.D. is a Technical Advisor in the Intellectual Property Practice Group of Duane Morris. Dr. Samson assists attorneys with the prosecution of patent applications.
Dr. Samson is a cancer biologist whose research focused on inflammation in melanoma and autoinflammatory skin disorders. Prior to joining the firm, she was a Scientist with Rancho Biosciences where she performed data modeling, curation, model alignment and FAIR-compliant data harmonization for various big pharma clients. She has nine years of laboratory experience with proficiencies in molecular biology techniques, protein and cell-based assays and data analysis.
Dr. Samson received a Ph.D. in Cancer Biology from The University of Colorado Anschutz Medical Campus and a B.A. in Biochemistry from the University of Washington.
Education
- The University of Colorado Anschutz Medical Campus, Ph.D., Cancer Biology, 2020
- University of Washington, B.A., Biochemistry, 2012
Experience
- Duane Morris LLP
- Technical Advisor, 2022-present - Rancho Biosciences
- Data Curation Scientist, 2020-2022
Selected Publications
- National Library of Medicine – National Center for Biotechnology Information List of Publications
- Zhai Z, Vaddi PK, Samson JM, Takegami T, Fujita M. NLRP1 Functions Downstream of the MAPK/ERK Signaling via ATF4 and Contributes to Acquired Targeted Therapy Resistance in Human Metastatic Melanoma. Pharmaceuticals (Basel). 2020 Dec 30;14(1). doi: 10.3390/ph14010023. PubMed PMID: 33396632; PubMed Central PMCID: PMC7823742.
- Samson JM, Ravindran Menon D, Vaddi PK, Kalani Williams N, Domenico J, Zhai Z, Backos DS, Fujita M. Computational Modeling of NLRP3 Identifies Enhanced ATP Binding and Multimerization in Cryopyrin-Associated Periodic Syndromes. Front Immunol. 2020;11:584364. doi: 10.3389/fimmu.2020.584364. eCollection 2020. PubMed PMID: 33329557; PubMed Central PMCID: PMC7711157.
- Zhai Z, Samson JM, Yamauchi T, Vaddi PK, Matsumoto Y, Dinarello CA, Ravindran Menon D, Fujita M. Inflammasome Sensor NLRP1 Confers Acquired Drug Resistance to Temozolomide in Human Melanoma. Cancers (Basel). 2020 Sep 4;12(9). doi: 10.3390/cancers12092518. PubMed PMID: 32899791; PubMed Central PMCID: PMC7563249.
- Samson JM, Ravindran Menon D, Smith DE, Baird E, Kitano T, Gao D, Tan AC, Fujita M. Clinical implications of ALDH1A1 and ALDH1A3 mRNA expression in melanoma subtypes. Chem Biol Interact. 2019 Dec 1;314:108822. doi: 10.1016/j.cbi.2019.108822. Epub 2019 Sep 30. PubMed PMID: 31580832; PubMed Central PMCID: PMC6916670.
- Ravindran Menon D, Luo Y, Arcaroli JJ, Liu S, KrishnanKutty LN, Osborne DG, Li Y, Samson JM, Bagby S, Tan AC, Robinson WA, Messersmith WA, Fujita M. CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma. Cancer Res. 2018 Dec 1;78(23):6561-6574. doi: 10.1158/0008-5472.CAN-18-0330. Epub 2018 Oct 8. PubMed PMID: 30297536; PubMed Central PMCID: PMC6279496.
- Zhai Z, Liu W, Kaur M, Luo Y, Domenico J, Samson JM, Shellman YG, Norris DA, Dinarello CA, Spritz RA, Fujita M. NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing apoptosis in metastatic melanoma. Oncogene. 2017 Jul 6;36(27):3820-3830. doi: 10.1038/onc.2017.26. Epub 2017 Mar 6. PubMed PMID: 28263976; PubMed Central PMCID: PMC5501746.
- Whidbey C, Vornhagen J, Gendrin C, Boldenow E, Samson JM, Doering K, Ngo L, Ezekwe EA Jr, Gundlach JH, Elovitz MA, Liggitt D, Duncan JA, Adams Waldorf KM, Rajagopal L. A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury. EMBO Mol Med. 2015 Apr;7(4):488-505. doi: 10.15252/emmm.201404883. PubMed PMID: 25750210; PubMed Central PMCID: PMC4403049.
- Laszlo AH, Derrington IM, Ross BC, Brinkerhoff H, Adey A, Nova IC, Craig JM, Langford KW, Samson JM, Daza R, Doering K, Shendure J, Gundlach JH. Decoding long nanopore sequencing reads of natural DNA. Nat Biotechnol. 2014 Aug;32(8):829-33. doi: 10.1038/nbt.2950. Epub 2014 Jun 25. PubMed PMID: 24964173; PubMed Central PMCID: PMC4126851.
- Laszlo AH, Derrington IM, Brinkerhoff H, Langford KW, Nova IC, Samson JM, Bartlett JJ, Pavlenok M, Gundlach JH. Detection and mapping of 5-methylcytosine and 5-hydroxymethylcytosine with nanopore MspA. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18904-9. doi: 10.1073/pnas.1310240110. Epub 2013 Oct 28. PubMed PMID: 24167255; PubMed Central PMCID: PMC3839702.